negatively regulates negatively regulates peptidase activity modulation by symbiont of host cellular process negative regulation by symbiont of host catalytic activity negative regulation by symbiont of host peptidase activity down-regulation by symbiont of host protease activity GO:0052054 negative regulation by symbiont of host protease activity down regulation by symbiont of host protease activity Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction. biological_process downregulation by symbiont of host protease activity inhibition of host protease activity inhibition by symbiont of host protease activity modulation by symbiont of host molecular function modulation by symbiont of host peptidase activity negative regulation of peptidase activity in other organism involved in symbiotic interaction