regulates regulates molecular_function modulation by symbiont of host process modulation by symbiont of host molecular function modification by symbiont of host protein function biological_process The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction. modification by symbiont of host molecular function GO:0052055 modulation of molecular function in other organism involved in symbiotic interaction regulation of molecular function