has part has_specified_input has_specified_output achieves_planned_objective statistical hypothesis test objective data transformation false positive rate hypergeometric distribution goodness of fit statistical test goodness of fit testing objective hypergeometric test Added following a term request by Chris Mungall: https://github.com/ISA-tools/stato/issues/6 Alejandra Gonzalez-Beltran Orlaith Burke Philippe Rocca-Serra http://www.ncbi.nlm.nih.gov/pubmed/?term=17182697 Bioinformatics. 2007 Feb 15;23(4):401-7. Enrichment or depletion of a GO category within a class of genes: which test? Rivals I1, Personnaz L, Taing L, Potier MC. hypergeometric test is a null hypothesis test which evaluates if a random variable follows a hypergeometric distribution. It is a test of goodness of fit to that distribution. The test is suited for situation aimed at assessing cases of sampling from a finite set without replacements. For instance, testing for enrichment or depletion of elements (e.g GO categories, genes) phyper(q, m, n, k, lower.tail = TRUE, log.p = FALSE) lower.tail logical; if TRUE (default), probabilities are P[X ≤ x], otherwise, P[X > x]. http://stat.ethz.ch/R-manual/R-patched/library/stats/html/Hypergeometric.html two tailed test absence of enrichment hypothesis absence of depletion hypothesis p-value ready for release