neurodegenerative pathway Parkinson's disease pathway KEGG:05012 One of the most common neurodegenerative diseases that is characterized by the loss of dopaminergic neurons in the substantia nigra and the presence of cytoplasmic inclusions called Lewy bodies in surrounding neurons. Several pathways are thought to be deregulated; for instance, imbalance of iron homeostasis is believed to contribute to the pathogenesis of the condition. PW:0000018 Parkinson disease pathway paralysis agitans pathway pathway