Notch signaling pathway PW:0000204 Signaling by NOTCH The Notch signaling pathway regulates processes involved in early embryonic development. It plays an important role in cell fate determination. Target genes of Notch have been implicated in angiogenesis, somitogenesis and gliogenesis. Deregulation of the Notch signaling pathway underlies a broad spectrum of diseases and clinical conditions. pathway cell-cell signaling pathway signaling pathway pertinent to development glycoprotein signaling pathway