part_of metabolic pathway of other amino acids homocysteine metabolic pathway Hcy metabolism Homocysteine (Hcy) metabolism is at the intersection of two pathways: the remethylation pathway that regenerates methionine and thus the methionine cycle and the transsulfuration pathway that gives rise to cysteine and derivatives. The Hcy pathway also engages choline, folate and vitamin metabolism and links to the metabolism of other amino acids and compounds. PW:0000398 homocysteine metabolic process pathway S-adenosylmethionine homeostasis pathway