signaling pathway pertinent to the brain and nervous system growth factor signaling pathway neurotrophic factor signaling pathway KEGG:04722 PW:0000571 Signaling pathways activated by members of the neurotrophic family of growth factors are involved in differentiation of progenitor cells, survival and differentiation of neural cells. They exert their effects by engaging specific tropomyosin-related kinase (Trk) receptors. pathway