celecoxib drug pathway 2010-03-17T08:51:56Z PW:0000761 The pharmacokinetics and pharmacodynamics pathway of celecoxib, a selective cyclooxygenase 2 inhibitor used for the treatment of osteoarthritis and rheumatoid arthritis. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. celebrex pathway pathway vpetri musculo-skeletal system drug pathway