ketone bodies metabolic pathway ketone bodies degradation pathway 2010-05-20T01:23:02Z PW:0000777 Those metabolic reactions that convert acetoacetate and beta-hydroxybutyrate back to acetyl-CoA, which then can enter the citrate cycle for energy production. Ketone bodies are synthesized in the liver and released into the bloodstream to supply fuel to peripheral tissues, heart and skeletal muscle in particular and during starvation, the brain. Utilization of Ketone Bodies ketone body catabolic process pathway vpetri