Toll-like receptor signaling pathway 2010-10-27T11:29:27Z PW:0000814 TLR signaling pathway Toll-Like Receptors Cascades Toll-like receptors represent a large and the better understood family of pattern recognition receptors that sense an array of exogenous structures, and recent evidence shows they can also recognize defective endogenous molecules. The intracellular signaling cascades they set in motion lead to the expression of inflammatory mediators. pathway vpetri pattern recognition receptor mediated signaling pathway