chemokine mediated signaling pathway CX3C chemokine mediated signaling pathway 2010-11-12T05:03:05Z PW:0000833 The CX3X family of chemokine is small and characterized by the presence of three residues separating the first two cysteines. Currently, only one member is known in mammals. Chemokines signal via G-protein coupled receptors to engage distinct G protein signaling and downstream cascades. VPetri pathway