cortisol signaling pathway altered transcription factor mediated signaling pathway altered cortisol signaling pathway 2011-08-23T09:15:01Z A cortisol signaling pathway that deviates from what its normal course should be. Mutations in the glucocorticoid receptor have been associated with rare, sporadic or familial, glucocorticoid resistance. PW:0000879 pathway vpetri altered glucocorticoid signaling pathway altered transcription pathway via transcription factor mediated signaling