amino acid metabolic pathway hydrophilic amino acid metabolic pathway 2012-07-31T10:39:29Z PW:0001075 Those metabolic reactions involving hydrophilic, polar amino acids. The hydrophilic amino acids include the negatively charged (acidic) aspartic acid and glutamic acid whose salts are glutamate and aspartate, respectively, the positively charged (basic) lysine and arginine and the uncharged polar asparagine, cysteine, glutamine, serine and threonine. Histidine, whose side chain contains an imidazole can shift from positively charged to neutral. pathway vpetri