homeostasis pathway acid-base homeostasis pathway 2012-10-04T12:58:08Z PW:0001103 The pathways that respond to and control the levels of protons, bicarbonate, carbon dioxide and ammonia in cells. Several sensing pathways, i.e., prompting intracellular signaling cascades and transport have been identified as critical players. The kidneys play a major role along with the respiratory system. pathway vpetri