part_of acid-base homeostasis pathway acid and base sensing signaling pathway bicarbonate sensing signaling pathway 2012-10-04T13:43:43Z PW:0001106 The signaling pathway elicited by increased levels of bicarbonate. Bicarbonate results from the instantaneous dissociation of carbonic acid, the end product of carbonic anhydrase hydration of exogenous or metabolically produced carbon dioxide. pathway vpetri