axitinib drug pathway axitinib pharmacodynamics pathway 2012-10-19T11:50:16Z PW:0001125 The pathway of axitinib-target interaction and of the biochemical or physiological responses to drug. Axitinib is a receptor tyrosine kinase inhibitor used in the treatment of renal cell carcinoma as well as other tumors. Axitinib is a selective second generation inhibitor of vascular endothelial growth factor receptors 1, 2 and 3. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri