part_of calcium homeostasis pathway parathyroid hormone signaling pathway 2012-11-01T09:32:46Z PTH signaling pathway PW:0001135 Parathyroid hormone (PTH) signaling is important for calcium and phosphate homeostasis in bone and kidney. It acts to increase the concentration of calcium in the blood, has both anabolic and catabolic effects in the bone and regulates calcium and phosphate reabsorption in the kidney. It also plays important roles in vitamin D metabolism. pathway vpetri parathyroid hormone family signaling pathway phosphate homeostasis pathway