tuberoinfundibular 39 residues peptide signaling pathway 2013-01-28T14:00:14Z PTH2 signaling pathway PW:0001171 Tip39 signaling pathway Tuberoinfundibular peptide of 39 residues (Tip39) is encoded by the parathyroid hormone 2 gene, weakly homologous to parathyroid hormone (PTH) and parathyroid hormone-like hormone (PTHrP). Tip39 is an endogenous ligand for the parathyroid hormone receptor 2, a G protein coupled receptor (GPCR), initially considered an orphan receptor. Signaling, mostly in the brain but also in the pancreas, testis and renal tissues, appears to involve elevation in cAMP. pathway vpetri parathyroid hormone family signaling pathway