plevitrexed drug pathway plevitrexed pharmacodynamics pathway 2013-04-05T09:19:15Z PW:0001212 The pathway of plevitrexed-target interactions and of the biochemical or physiological responses to drug. The drug is an antifolate that targets thymidylate synthase and is used in the treatment of several cancers. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri