prostanoid signaling pathway prostaglandin signaling pathway 2013-05-14T12:40:57Z PW:0001297 Prostaglandins are one of several families of prostanoids, eicosanoids derived from omega-3 or omega-6 fatty acids. Of the several prostaglandins, prostaglandin E2 signaling via four distinct receptors mediates a broad range of physiological effects. Others include prostaglandin D2 with various central nervous system (CNS) activities and prostaglandin I2 or prostacyclin with important vascular functions. pathway vpetri