transcription factor mediated signaling pathway transcription pathway via transcription factor mediated signaling basic helix-loop-helix signaling pathway 2013-06-19T11:06:19Z Basic helix-loop-helix proteins represent a large superfamily of transcription factors that regulate the expression of genes involved in growth and development as well as environmental responses. Phylogenetically, they are classified into six clades of which the sixth, also referred to as clade F only contains plant genes. PW:0001371 pathway vpetri