cardiovascular system drug pathway ezetimibe drug pathway 2013-08-26T09:32:29Z PW:0001443 The pharmacokinetics and pharmacodynamics pathway of ezetimibe - a drug used to lower the plasma cholesterol level. Ezetimibe is a selective cholesterol absorption inhibitor used both as monotherapy and in combination with statins. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. Zetia drug pathway pathway vpetri