doxorubicin drug pathway 2013-08-29T15:06:28Z PW:0001455 The pharmacokinetics and pharmacodynamics pathway of doxorubicin, a streptomyces metabolite used as a chemotherapeutic agent used in the treatment of cancers. However, its use is limited by the serious cardiotoxic side effects. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri antineoplastic drug pathway