sensory system disease pathway Usher syndrome pathway 2014-02-14T10:52:27Z PW:0001506 The Usher syndrome is characterized by both vision and hearing loss. One sixth of patients with retinitis pigmentosa also have Usher syndrome. Clinically, there are three types of Usher syndromes that vary in terms of severity and onset. The genes involved are located in inner ear hair cells and the connecting cilium of photoreceptor cells. Their associations with auditory mechanotransduction are better known but their roles in visual phototransduction and altered pathways are still to be delineated. pathway vpetri