platinum (Pt) containing drug pathway cisplatin drug pathway 2014-02-26T10:16:42Z PW:0001508 The pharmacokinetics/pharmacodynamics of cisplatin, a platinum (Pt) containing drug widely used in the treatment of solid tumors. Cisplatin is the most potent of such drugs, it si also the one with the strongest toxic side effects. Nephorotoxicity and ototoxicity are among the primary toxic side effects. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri