toxin and toxicant response pathway platinum (Pt) containing drug response pathway 2014-02-26T10:23:49Z A pathway triggered by exposure to platinum (Pt) containing drugs used in the treatment of solid tumors. The DNA lesion they introduce is toxic to the tumor cells. However, they also exert powerful toxic side effects. Cisplatin, the most potent drug is also the most toxic followed by the less potent carboplatin. PW:0001509 pathway vpetri