prostanoid signaling pathway thromboxane A2 signaling pathway 2014-04-18T11:05:02Z PW:0001527 Thromboxane is one of several families of prostanoids, eicosanoids derived from omega-3 or omega-6 fatty acids. Of the two thromboxane molecules, only A2 has activity. Thromboxane A2 signaling exerts vasoconstrictor and platelet aggregation roles. Its actions oppose those of prostaglandin I2, the other important prostanoid for cardiovascular system homeostasis. Thromboxane signalling through TP receptor pathway thromboxane A2 signaling pathway vpetri