amiloride drug pathway amiloride pharmacodynamics pathway 2015-02-26T15:23:37Z PW:0001640 SMP:00133 The pathway of amiloride-target interaction and of the biochemical or physiological responses to drug. The drug blocks the epithelial sodium channels and is used in the treatment of hypertension and congestive heart failure. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri