anistreplase drug pathway 2015-03-09T15:22:18Z PW:0001662 The pharmacokinetics and pharmacodynamics pathway of anistreplase, an antithrombic drug that converts plasminogen to the active plasmin which degrades fibrin (blood clots). Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri thrombolytic drug pathway