vinblastine drug pathway vinblastine pharmacodynamics pathway 2015-05-08T09:35:29Z PW:0001678 SMP:00436 The pathway of vinblastine-target interaction and of the biochemical or physiological responses to drug. The drug interacts with tubulin and disrupts microtubules function, particularly those at the mitotic spindle. Genetic variations can cause differences in the response of the organism to the drug. VBL pharmacodynamics pathway pathway vpetri