adrenergic beta receptor antagonist drug pathway adrenergic beta receptor non-selective antagonist drug pathway 2015-06-12T09:59:01Z PW:0001738 The pharmacokinetics and pharmacodynamics pathway of non-selective adrenergic beta receptors blockers. Adrenergic beta receptors, in response to epinephrine or norepinephrine couple to the Gs alpha subunit of heterotrimeric G protein to elicit several responses. Beta receptor antagonists are used to inhibit these responses. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri