chemical compound signaling pathway radical mediated signaling pathway 2015-07-29T09:05:15Z PW:0001764 The signaling pathway initiated by a radical. The reactivity of free radicals renders them potentially hazardous but it can also positively contribute to many biological processes. The generation, utilization and neutralization of radicals is tightly regulated. Disturbance in the levels and regulation of radicals leads to pathological states including cardiovascular diseases, diabetes, cancer and aging. pathway vpetri