musculo-skeletal system drug pathway nabumetone drug pathway 2015-09-17T13:44:05Z PW:0001922 The pharmacokinetics and pharmacodynamics pathway of nabumetone, a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase enzymes, preferentially COX-2 type. The drug is used in the treatment of inflammation and pain. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri