mercaptopurine drug pathway mercaptopurine pharmacodynamics pathway 2015-09-22T14:30:57Z PW:0001944 SMP:00428 The pathway of mercaptopurine-target interaction and of the biochemical or physiological responses to drug. The drug is used as an immunosuppressive and its cytotoxic effects result from its interference with nucleic acids synthesis and function. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri