furosemide drug pathway 2015-10-02T13:13:00Z PW:0002014 The pharmacokinetics and pharmacodynamics pathway of furosemide - a blocker of luminal sodium-potassium-chloride symporter used for the treatment of hypertension and edema. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri diuretic drug pathway