diflunisal drug pathway diflunisal pharmacodynamics pathway 2015-10-21T08:53:42Z PW:0002081 SMP:00289 The pathway of diflunisal-target interaction and of the biochemical or physiological responses to drug. Diflunisal is an inhibitor of cyclooxygenase enzymes used in the treatment of pain and inflammation. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri