reteplase drug pathway reteplase pharmacodynamics pathway 2015-11-20T10:47:55Z PW:0002258 SMP:00285 The pathway of reteplase-target interaction and of the biochemical or physiological responses to drug. Reteplase is one of several recombinant tissue plasminogen activators. Reteplase is used to treat heart attack. Genetic variations can cause differences in the response of the organism to the drug. pathway vpetri