antineoplastic drug pathway tioguanine drug pathway 2015-12-29T12:59:05Z PW:0002392 The pharmacokinetics and pharmacodynamics pathway of tioguanine, a drug used to treat several leukemia types, ulcerative colitis and some autoimmune diseases. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway thioguanine drug pathway vpetri