endosomal sorting pathway degradative endosome sorting pathway 2016-01-12T15:06:00Z PW:0002400 The lysosome is the final destination of endosomal degradative and autophagy pathways. Fusion of late endosomes and mature autophagosome with the lysosome form the endolysosome or autolysosome, respectively, where cargo is actively degraded. pathway vpetri