anesthetic drug pathway levobupivacaine drug pathway 2016-01-25T15:24:47Z PW:0002440 The pharmacokinetics and pharmacodynamics pathway of levobupivacaine, a drug used as a local anesthetic. It is the S-enantiomer of bupivacaine compared to which, it has a longer duration of action and is associated with less vasodilation. Genetic variations can result in changes in drug availability and can cause differences in the response of the organism to the drug. pathway vpetri