dopamine metabolic pathway catecholamine degradation pathway dopamine degradation pathway 2016-02-16T11:10:38Z PW:0002511 Those metabolic reactions involved in the degradation of dopamine. Dopamine degradation can be initiated by two enzymes. Dopamine can spontaneously oxidize and in the process, radicals are being produced. Storage of newly synthesized dopamine or degradation of excess cytosolic dopamine prevents oxidation of dopamine. dopamine catabolic process pathway vpetri