nicotinamide adenine nucleotide utilization pathway ADP-ribosylation pathway, mono and poly-ribosylation 2016-06-02T15:13:11Z Mono- and poly-ADP-ribosylation of proteins is carried out by members of the PARP family. Proteins with particular domains or modules are involved in the recognition of modified proteins while others reverse the modification. Protein ADP-ribosylation plays important roles in DNA damage repair, cell-cycle, transcription and cell death pathways. PW:0002582 pathway vpetri