toxin and toxicant response pathway acrolein response pathway 2016-10-20T13:11:04Z Acrolein is a reactive unsaturated aldehyde that is a dietary and environmental pollutant and can also be metabolically generated. It exerts severe toxic effects through production of DNA and protein adducts and disruption of important cellular pathways. Acrolein is thought to play a role in cardiovascular and neurodegenerative diseases, diabetes and immune disorders. PW:0002640 pathway vpetri