cellular senescence pathway oncogene-induced cell senescence pathway 2023-11-09T15:23:41Z A cellular senescence pathway associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family, which can be caused by oncogenic mutations in RAS or RAF proteins, or by oncogenic mutations in growth factor receptors, such as EGFR, that act upstream of RAS/RAF/MAPK cascade. Oncogene Induced Senescence PW:0002671 gthayman oncogene-induced cell senescence pathway