muscle contraction pathway striated muscle contraction pathway 2024-06-05T16:29:11Z A pathway in which force is generated within striated muscle tissue, resulting in a change in muscle geometry. Force generation involves a calcium-triggered chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle contains repeating units (sarcomeres) of the contractile myofibrils that are arranged in registry throughout the cell, resulting in transverse or oblique striations observable by light microscope. PW:0002683 Striated Muscle Contraction gthayman pathway