part_of RNA polymerase II transcription pathway RNA polymerase II promoter clearance pathway 2025-05-13T13:59:32Z PW:0002736 RNA Polymerase II Transcription Initiation And Promoter Clearance RNA polymerase II promoter clearance The series of events mediating the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors. gthayman pathway