part_of part of is part of part of has part has part has_part deep to superficial to develops from composed primarily of immediate transformation of elastic fiber Homo sapiens skin epidermis dermis http://upload.wikimedia.org/wikipedia/commons/2/23/EpidermisPainted.svg MIAA:0000153 corium EMAPA:17527 When approaching controversies surrounding skin evolution, we need to remember that the skin consists of two layers, an epidermis and a dermis, not a single evolving structure. (...) It is little wonder that controversies about homology exist. If we think of the epidermis, the dermis, and their interactions as an evolving unit, then their specialized products (hair, feathers, and reptilian scales) are broadly homologous.[well established][VHOG] MESH:D020405 GAID:1321 ZFA:0001119 A collagenous layer of the skin subjacent to the epidermis and covering the hypodermis. It contains various types of cells (e.g. fibroblasts, pigment cells, nerve, blood vessels and scales. Le Guellec et al, 2004.[TAO] cutis MA:0000152 CALOHA:TS-2076 NCIT:C12701 dermal AAO:0000128 XAO:0000217 BTO:0000294 FMA:70323 uberon EFO:0000953 MAT:0000153 Consider adding a layer-of-skin grouping class for all skin layers TAO:0001119 UBERON:0002067 EV:0100154 The dermis is a layer of skin between the epidermis (with which it makes up the skin) and subcutaneous tissues, and is composed of two layers, the papillary and reticular dermis[WP]. VHOG:0000108 vertebrate dermis UMLS:C0011646 hypodermis skin of body connective tissue ectoderm-derived structure future dermis structure with developmental contribution from neural crest collection of collagen fibrils integumentary system layer