valid_for_go_ontology
valid_for_go_annotation_extension
valid_for_gocam
negatively regulates
directly regulates
directly negatively regulates
https://wiki.geneontology.org/Directly_negatively_regulates
directly negatively regulates (process to process)
p directly negatively regulates q iff p is immediately causally upstream of q, and p negatively regulates q.