has specified product has specified reactant indoles nitrotoluene indole synthesis Leimgruber-Batcho indole synthesis 2021-12-03T14:45:01Z Batcho-Leimgruber indole synthesis Condensation of a formamide acetal with a derivative of o-nitrotoluene to yield an enamine intermediate that subsequently undergoes reductive cyclization to give the corresponding indole. RXNO RXNO:0000672