diagnosed using tool treated with in guideline Acute Chest Syndrome This definition was given by the WG: 'Acute onset of respiratory symptoms and/or signs and an X-ray consistent with alveolar consolidation but not atelectasis, involving at least one complete lung segment." With this definition source:The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell Disease. O. Castro, D. J. Brambilla, B. Thorington, C. A. Reindorf, R. B. Scott, P. Gillette, J. C. Vera, P. S. Levy Blood. 1994 Jul 15; 84(2): 643–649. However, the definition did not seem to come from this source, so the DO term was used instead. Sufficient From the DO: The disease has_symptom fever, has_symptom pleuritic chest pain, has_symptom tachypnea, has_symptom cough, has_symptom hypoxemia, has_symptom marked leukocytosis, has_symptom marked leukocytosis, and has_symptom diffuse infiltrates on chest radiograph. DOID:1584 Acute Chest Syndrome in Sickle Cell Disease SCDO:0000015 A lung disease that involves a vasoocclusive crisis of the pulmonary vasculature seen in patients with sickle cell anemia. The crisis is initiated by a lung infection, and the resulting inflammation and loss of oxygen tension leads to sickling of red cells and further vasoocclusion. Abnormality of the Respiratory System Gene Therapy Personal Medical History Antibiotic Blood Transfusion Chest X-Ray Hematopoietic Stem Cell Transplantation Hydration Therapy Hydroxyurea Physical Examination Physiotherapy Acute Phenotype Recommendations for the Management of Sickle Cell Disease in South Africa National Guideline for the Control and Management of Sickle Cell Disease Management of Sickle Cell Disease - The United Republic of Tanzania A Parental Guide to Managing Sickle Cell Disease Standards for Clinical Care of Adults with Sickle Cell Disease in the UK Sickle Cell Disease: The Clinical Care Guidelines of the Sickle Cell Unit Consensus Statement on the Care of Patients with Sickle Cell Disease in Canada Sickle Cell Disease in Children, Standards and Guidelines for Clinic Care Evidence-Based Management of Sickle Cell Disease Management of Children with Sickle Cell Disease in Europe: Current Situation and Future Perspectives ENERCA Clinical Recommendations for Disease Management and Prevention of Complications of Sickle Cell Disease in Children